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Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease
Reduced expression of GM1 and other major brain gangliosides GD1a, GD1b and GT1b have been reported in Parkinson’s disease (PD) brain. Mechanisms underlying these changes are unclear but may be due to a deficit in the ganglioside biosynthetic process. The present study examined the extent to which d...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002063/ https://www.ncbi.nlm.nih.gov/pubmed/29902255 http://dx.doi.org/10.1371/journal.pone.0199189 |