Cargando…
Lack of complex type N-glycans lessens aberrant neuronal properties
Modifications in surface glycans attached to proteins via N-acetylglucosamine-β1-N-asparagine linkage have been linked to tumor development and progression. These modifications include complex N-glycans with high levels of branching, fucose and sialic acid residues. Previously, we silenced Mgat2 in...
Autores principales: | Hall, M. Kristen, Weidner, Douglas A., Whitman, Austin A., Schwalbe, Ruth A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002081/ https://www.ncbi.nlm.nih.gov/pubmed/29902282 http://dx.doi.org/10.1371/journal.pone.0199202 |
Ejemplares similares
-
Predominant Expression of Hybrid N-Glycans Has Distinct Cellular Roles Relative to Complex and Oligomannose N-Glycans
por: Hall, M. Kristen, et al.
Publicado: (2016) -
Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells
por: Hall, M. Kristen, et al.
Publicado: (2015) -
Membrane Distribution and Activity of a Neuronal Voltage-Gated K+ Channel is Modified by Replacement of Complex Type N-Glycans with Hybrid Type
por: Hall, M Kristen, et al.
Publicado: (2017) -
Cell surface N-glycans influence the level of functional E-cadherin at the cell–cell border
por: Hall, M. Kristen, et al.
Publicado: (2014) -
Knockdown of N-Acetylglucosaminyltransferase-II Reduces Matrix Metalloproteinase 2 Activity and Suppresses Tumorigenicity in Neuroblastoma Cell Line
por: Hall, M. Kristen, et al.
Publicado: (2020)