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Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling

Recognition of Pathogen-associated Molecular Patterns (PAMPs) by Toll-like receptors is central to innate immunity. Many bacterial PAMPs such as lipopolysaccharide (LPS) and lipoteichoic acid have amphiphilic properties. The hydrophobicity of amphiphilic PAMPs contributes to increasing entropy and c...

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Detalles Bibliográficos
Autores principales: Stromberg, Loreen R., Mendez, Heather M., Kubicek-Sutherland, Jessica Z., Graves, Steven W., Hengartner, Nicolas W., Mukundan, Harshini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002092/
https://www.ncbi.nlm.nih.gov/pubmed/29902192
http://dx.doi.org/10.1371/journal.pone.0198531