miR-146a deficiency in hematopoietic cells is not involved in the development of atherosclerosis

BACKGROUND: Atherosclerosis involves activation of the IRAK1/TRAF6/NF-κB inflammatory cascade, which is negatively regulated by miR146a. Previous studies showed that the TT genotype of rs2431697, located near the miR-146a gene, drives lower miR-146a transcription and predicts adverse cardiovascular...

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Detalles Bibliográficos
Autores principales: del Monte, Alberto, Arroyo, Ana B., Andrés-Manzano, María J., García-Barberá, Nuria, Caleprico, María S., Vicente, Vicente, Roldán, Vanessa, González-Conejero, Rocío, Martínez, Constantino, Andrés, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002112/
https://www.ncbi.nlm.nih.gov/pubmed/29902229
http://dx.doi.org/10.1371/journal.pone.0198932

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