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Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition

The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mutants with changes in their cell wall, we identifi...

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Detalles Bibliográficos
Autores principales: Esher, Shannon K., Ost, Kyla S., Kohlbrenner, Maria A., Pianalto, Kaila M., Telzrow, Calla L., Campuzano, Althea, Nichols, Connie B., Munro, Carol, Wormley, Floyd L., Alspaugh, J. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002136/
https://www.ncbi.nlm.nih.gov/pubmed/29864141
http://dx.doi.org/10.1371/journal.ppat.1007126