Cargando…

Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition

The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. In a genetic screen for mutants with changes in their cell wall, we identifi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Esher, Shannon K., Ost, Kyla S., Kohlbrenner, Maria A., Pianalto, Kaila M., Telzrow, Calla L., Campuzano, Althea, Nichols, Connie B., Munro, Carol, Wormley, Floyd L., Alspaugh, J. Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002136/ https://www.ncbi.nlm.nih.gov/pubmed/29864141 http://dx.doi.org/10.1371/journal.ppat.1007126

Ejemplares similares

An Immunogenic and Slow-Growing Cryptococcal Strain Induces a Chronic Granulomatous Infection in Murine Lungs
por: Telzrow, Calla L., et al.
Publicado: (2022)

A Fungal Arrestin Protein Contributes to Cell Cycle Progression and Pathogenesis
por: Telzrow, Calla L., et al.
Publicado: (2019)

Roles for Stress Response and Cell Wall Biosynthesis Pathways in Caspofungin Tolerance in Cryptococcus neoformans
por: Pianalto, Kaila M., et al.
Publicado: (2019)

HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence
por: Brandão, Fabiana, et al.
Publicado: (2018)

Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation
por: Ost, Kyla S., et al.
Publicado: (2017)

Cryptococcus neoformans Mar1 function links mitochondrial metabolism, oxidative stress, and antifungal tolerance
por: Telzrow, Calla L., et al.
Publicado: (2023)

Innate Immunity against Cryptococcus, from Recognition to Elimination
por: Campuzano, Althea, et al.
Publicado: (2018)

New Horizons in Antifungal Therapy
por: Pianalto, Kaila M., et al.
Publicado: (2016)

Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
por: Esher, Shannon K., et al.
Publicado: (2016)

Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries
por: Telzrow, Calla L, et al.
Publicado: (2021)

The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator
por: Ost, Kyla S., et al.
Publicado: (2015)

Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi
por: Brown, Hannah E., et al.
Publicado: (2020)

Dectin-3 Is Not Required for Protection against Cryptococcus neoformans Infection
por: Campuzano, Althea, et al.
Publicado: (2017)

Cryptococcal pathogenic mechanisms: a dangerous trip from the environment to the brain
por: Esher, Shannon K, et al.
Publicado: (2018)

Induction of memory-like dendritic cell responses in vivo
por: Hole, Camaron R., et al.
Publicado: (2019)

CARD9 Is Required for Classical Macrophage Activation and the Induction of Protective Immunity against Pulmonary Cryptococcosis
por: Campuzano, Althea, et al.
Publicado: (2020)

Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans
por: Ballou, Elizabeth Ripley, et al.
Publicado: (2013)

IFN-γ immune priming of macrophages in vivo induces prolonged STAT1 binding and protection against Cryptococcus neoformans
por: Leopold Wager, Chrissy M., et al.
Publicado: (2018)

Intracellular trafficking and signaling in development
por: Constam, Daniel B
Publicado: (2009)

Intracellular Trafficking of HBV Particles
por: Jiang, Bingfu, et al.
Publicado: (2020)

Intracellular trafficking pathways for plasmid DNA complexed with highly efficient endosome escape polymers
por: Gillard, Marianne, et al.
Publicado: (2015)

pH Response Pathways in Fungi: Adapting to Host-derived and Environmental Signals
por: Selvig, Kyla, et al.
Publicado: (2011)

A sustained passion for intracellular trafficking
por: Miller, Elizabeth A.
Publicado: (2013)

An Update on the Intracellular and Intercellular Trafficking of Carmoviruses
por: Navarro, José A., et al.
Publicado: (2017)

Intracellular Cholesterol Trafficking and Impact in Neurodegeneration
por: Arenas, Fabian, et al.
Publicado: (2017)

Intracellular Trafficking and Translocation of Pertussis Toxin
por: Teter, Ken
Publicado: (2019)

The Role of GSH in Intracellular Iron Trafficking
por: Hider, Robert, et al.
Publicado: (2021)

Sphingomyelin Synthases Regulate Protein Trafficking and Secretion
por: Subathra, Marimuthu, et al.
Publicado: (2011)

Intracellular trafficking of ceramide by ceramide transfer protein
por: Hanada, Kentaro
Publicado: (2010)

Impact of Photosensitizers Activation on Intracellular Trafficking and Viscosity
por: Aubertin, Kelly, et al.
Publicado: (2013)

Uptake and Intracellular Trafficking of Superantigens in Dendritic Cells
por: Ganem, María B., et al.
Publicado: (2013)

Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
por: Foroozandeh, Parisa, et al.
Publicado: (2018)

Getting there: Thyroid hormone receptor intracellular trafficking
por: Allison, Lizabeth A.
Publicado: (2021)

Craniofacial Diseases Caused by Defects in Intracellular Trafficking
por: Lu, Chung-Ling, et al.
Publicado: (2021)

Intracellular trafficking of HLA-E and its regulation
por: He, Wanlin, et al.
Publicado: (2023)

Trafficking of Sendai Virus Nucleocapsids Is Mediated by Intracellular Vesicles
por: Chambers, Raychel, et al.
Publicado: (2010)

Comparison of the Intracellular Trafficking Itinerary of CTLA-4 Orthologues
por: Kaur, Satdip, et al.
Publicado: (2013)

Abrin Immunotoxin: Targeted Cytotoxicity and Intracellular Trafficking Pathway
por: Gadadhar, Sudarshan, et al.
Publicado: (2013)

Intracellular calcium release modulates polycystin-2 trafficking
por: Miyakawa, Ayako, et al.
Publicado: (2013)

Impaired intracellular trafficking defines early Parkinson's disease
por: Hunn, Benjamin H.M., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_i96357mptpvul68u61r0851521