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Serine/Threonine Kinase CHEK1-Dependent Transcriptional Regulation of RAD54L Promotes Proliferation and Radio Resistance in Glioblastoma

Accumulating evidence indicates that Checkpoint kinase 1 (CHEK1) plays an essential role in tumor cells and that it could induce cell proliferation and could be related to prognosis in multiple types of cancer. However, the biological role and molecular mechanism of CHEK1 in GBM still remain unclear...

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Detalles Bibliográficos
Autores principales: Bai, Xiaobin, Wang, Jia, Huo, Longwei, Xie, Yuchen, Xie, Wanfu, Xu, Gaofeng, Wang, Maode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002345/
https://www.ncbi.nlm.nih.gov/pubmed/29287241
http://dx.doi.org/10.1016/j.tranon.2017.11.007