Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users

PURPOSE: The detection of a novel psychoactive substance, 2F-MT-45, a fluorinated analogue of the synthetic opioid MT-45, was reported in a single seized tablet. MT-45, 2F-, 3F- and 4F-MT-45 were synthesised and reference analytical data were reported. The in vitro and in vivo metabolisms of MT-45 a...

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Detalles Bibliográficos
Autores principales: McKenzie, Craig, Sutcliffe, Oliver B., Read, Kevin D., Scullion, Paul, Epemolu, Ola, Fletcher, Daniel, Helander, Anders, Beck, Olof, Rylski, Alexia, Antonides, Lysbeth H., Riley, Jennifer, Smith, Shannah A., Nic Daeid, Niamh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002428/
https://www.ncbi.nlm.nih.gov/pubmed/29963206
http://dx.doi.org/10.1007/s11419-018-0413-1

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