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Lower Expression of Ndfip1 Is Associated With Alzheimer Disease Pathogenesis Through Decreasing DMT1 Degradation and Increasing Iron Influx
We have previously reported that high expression of divalent metal transporter 1 (DMT1) plays a crucial role in iron dyshomeostasis and β-amyloid (Aβ) peptide generation in the brain of Alzheimer’s disease (AD). Recent studies have shown that Nedd4 family interacting protein 1 (Ndfip1) can degrade D...
Autores principales: | Tian, Juan, Zheng, Wei, Li, Xin-Lu, Cui, Yuan-Hong, Wang, Zhan-You |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002492/ https://www.ncbi.nlm.nih.gov/pubmed/29937728 http://dx.doi.org/10.3389/fnagi.2018.00165 |
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