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Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel–Lindau-Deficient Renal Cancer

The most common type of the renal cancers detected in humans is clear cell renal cell carcinomas (ccRCCs). These tumors are usually initiated by biallelic gene inactivation of the Von Hippel–Lindau (VHL) factor in the renal epithelium, which deregulates the hypoxia-inducible factors (HIFs) HIF1α and...

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Detalles Bibliográficos
Autores principales:	Meléndez-Rodríguez, Florinda, Roche, Olga, Sanchez-Prieto, Ricardo, Aragones, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002531/ https://www.ncbi.nlm.nih.gov/pubmed/29938199 http://dx.doi.org/10.3389/fonc.2018.00214

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