Cargando…

A Single Amino Acid in the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses

Influenza B virus (IBV) is one of the human respiratory viruses and one of the targets of seasonal vaccination. However, the bifurcation of two antigenically distinct lineages of IBVs makes it difficult to arrange proper medical countermeasures. Moreover, compared with pathogenicity-related molecula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bae, Joon-Yong, Lee, Ilseob, Kim, Jin Il, Park, Sehee, Yoo, Kirim, Park, Miso, Kim, Gayeong, Park, Mee Sook, Lee, Joo-Yeon, Kang, Chun, Kim, Kisoon, Park, Man-Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002706/ https://www.ncbi.nlm.nih.gov/pubmed/29643248 http://dx.doi.org/10.1128/JVI.00259-18

Ejemplares similares

Single PA mutation as a high yield determinant of avian influenza vaccines
por: Lee, Ilseob, et al.
Publicado: (2017)

Amino Acid Mutations A286V and T437M in the Nucleoprotein Attenuate H7N9 Viruses in Mice
por: Ma, Shujie, et al.
Publicado: (2020)

Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation In Vivo and In Ovo
por: Keep, Sarah, et al.
Publicado: (2022)

A Single Amino Acid at Position 431 of the PB2 Protein Determines the Virulence of H1N1 Swine Influenza Viruses in Mice
por: Xu, Chengzhi, et al.
Publicado: (2020)

A Single Amino Acid Substitution in the Novel H7N9 Influenza A Virus NS1 Protein Increases CPSF30 Binding and Virulence
por: Ayllon, Juan, et al.
Publicado: (2014)

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs
por: Wang, Zeng, et al.
Publicado: (2017)

Glycosylation generates an efficacious and immunogenic vaccine against H7N9 influenza virus
por: Kim, Jin Il, et al.
Publicado: (2020)

Zika Virus Infection Induces Interleukin-1β-Mediated Inflammatory Responses by Macrophages in the Brain of an Adult Mouse Model
por: Jeong, Gi Uk, et al.
Publicado: (2023)

Towards the Application of Human Defensins as Antivirals
por: Park, Mee Sook, et al.
Publicado: (2018)

Reassortment compatibility between PB1, PB2, and HA genes of the two influenza B virus lineages in mammalian cells
por: Kim, Jin Il, et al.
Publicado: (2016)

Adaptive mutations of neuraminidase stalk truncation and deglycosylation confer enhanced pathogenicity of influenza A viruses
por: Park, Sehee, et al.
Publicado: (2017)

Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses
por: Akiyama, Hisashi, et al.
Publicado: (2021)

Coinfection with SARS-CoV-2 and Influenza A Virus Increases Disease Severity and Impairs Neutralizing Antibody and CD4(+) T Cell Responses
por: Kim, Eun-Ha, et al.
Publicado: (2022)

Original Antigenic Sin Response to RNA Viruses and Antiviral Immunity
por: Park, Mee Sook, et al.
Publicado: (2016)

African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
por: Dodantenna, Niranjan, et al.
Publicado: (2022)

Contribution of SARS-CoV-2 Accessory Proteins to Viral Pathogenicity in K18 Human ACE2 Transgenic Mice
por: Silvas, Jesus A., et al.
Publicado: (2021)

The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus
por: Dong, Wenjuan, et al.
Publicado: (2022)

Hemagglutinin and Neuraminidase Antibodies Are Induced in an Age- and Subtype-Dependent Manner after Influenza Virus Infection
por: Wong, Sook-San, et al.
Publicado: (2020)

New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention, and Cure
por: Li, Hui, et al.
Publicado: (2021)

Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2-Infected Syrian Hamsters
por: Brocato, Rebecca L., et al.
Publicado: (2020)

Discovery and Selection of Hepatitis B Virus-Derived T Cell Epitopes for Global Immunotherapy Based on Viral Indispensability, Conservation, and HLA-Binding Strength
por: de Beijer, Monique T. A., et al.
Publicado: (2020)

Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice
por: Olivarria, Gema M., et al.
Publicado: (2022)

Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice
por: Lee, Wendy W. L., et al.
Publicado: (2015)

African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′3′-cGAMP
por: Ranathunga, Lakmal, et al.
Publicado: (2023)

Combination of CD8β Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques
por: McBrien, Julia B., et al.
Publicado: (2020)

Characterization of an Emergent Chicken H3N8 Influenza Virus in Southern China: a Potential Threat to Public Health
por: Chen, Peiwen, et al.
Publicado: (2023)

Caribbean and La Réunion Chikungunya Virus Isolates Differ in Their Capacity To Induce Proinflammatory Th1 and NK Cell Responses and Acute Joint Pathology
por: Teo, Teck-Hui, et al.
Publicado: (2015)

Heparanase Blockade as a Novel Dual-Targeting Therapy for COVID-19
por: Xiang, Jingyu, et al.
Publicado: (2022)

Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes
por: Umviligihozo, Gisele, et al.
Publicado: (2020)

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice
por: Wong, Ting Y., et al.
Publicado: (2022)

Impact of HLA Selection Pressure on HIV Fitness at a Population Level in Mexico and Barbados
por: Juarez-Molina, Claudia I., et al.
Publicado: (2014)

Virus and Host Factors Affecting the Clinical Outcome of Bluetongue Virus Infection
por: Caporale, Marco, et al.
Publicado: (2014)

Acute-Phase CD8 T Cell Responses That Select for Escape Variants Are Needed to Control Live Attenuated Simian Immunodeficiency Virus
por: Harris, Max, et al.
Publicado: (2013)

High Production Rates Sustain In Vivo Levels of PD-1(high) Simian Immunodeficiency Virus-Specific CD8 T Cells in the Face of Rapid Clearance
por: Petrovas, Constantinos, et al.
Publicado: (2013)

Regulatory T Cells Prevent Th2 Immune Responses and Pulmonary Eosinophilia during Respiratory Syncytial Virus Infection in Mice
por: Durant, Lydia R., et al.
Publicado: (2013)

Glycoprotein B Cleavage Is Important for Murid Herpesvirus 4 To Infect Myeloid Cells
por: Glauser, Daniel L., et al.
Publicado: (2013)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Immunosuppression Facilitates the Reactivation of Latent Papillomavirus Infections
por: Maglennon, G. A., et al.
Publicado: (2014)

Delayed Sequelae of Neonatal Respiratory Syncytial Virus Infection Are Dependent on Cells of the Innate Immune System
por: Harker, James A., et al.
Publicado: (2014)

Vaccinia Virus Inhibits NF-κB-Dependent Gene Expression Downstream of p65 Translocation
por: Sumner, Rebecca P., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_thnp0ovfgovu2cbqupr7jnhel1