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Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro

Native-like, soluble, recombinant SOSIP trimers of various designs and based on several env genes of human immunodeficiency virus type 1 (HIV-1) are being tested as immunogens in different animal models. These experiments almost always involve coformulating the trimers with an adjuvant to boost the...

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Detalles Bibliográficos
Autores principales: Ozorowski, Gabriel, Cupo, Albert, Golabek, Michael, LoPiccolo, Michelle, Ketas, Thomas A., Cavallary, Matt, Cottrell, Christopher A., Klasse, P. J., Ward, Andrew B., Moore, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002727/
https://www.ncbi.nlm.nih.gov/pubmed/29669838
http://dx.doi.org/10.1128/JVI.00381-18