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Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent
Antifungal agents for the treatment of Candida albicans infections are limited. We recently discovered a novel antifungal small molecule, SM21, with promising in vivo activity. Herein, we employed the newly developed C. albicans haploid toolbox to uncover the mechanism of action of SM21. Comprehensi...
Autores principales: | Truong, Thuyen, Suriyanarayanan, Tanujaa, Zeng, Guisheng, Le, Thuc D., Liu, Lin, Li, Jiuyong, Tong, Cao, Wang, Yue, Seneviratne, Chaminda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002804/ https://www.ncbi.nlm.nih.gov/pubmed/29938200 http://dx.doi.org/10.3389/fcimb.2018.00164 |
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