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PharmGKB: A worldwide resource for pharmacogenomic information

As precision medicine becomes increasingly relevant in healthcare, the field of pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading institutions have begun to implement PGx testing and the amount of published PGx literature increases yearly. The Pharmacogenomics...

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Detalles Bibliográficos
Autores principales: Barbarino, Julia M., Whirl‐Carrillo, Michelle, Altman, Russ B., Klein, Teri E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002921/
https://www.ncbi.nlm.nih.gov/pubmed/29474005
http://dx.doi.org/10.1002/wsbm.1417
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author Barbarino, Julia M.
Whirl‐Carrillo, Michelle
Altman, Russ B.
Klein, Teri E.
author_facet Barbarino, Julia M.
Whirl‐Carrillo, Michelle
Altman, Russ B.
Klein, Teri E.
author_sort Barbarino, Julia M.
collection PubMed
description As precision medicine becomes increasingly relevant in healthcare, the field of pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading institutions have begun to implement PGx testing and the amount of published PGx literature increases yearly. The Pharmacogenomics Knowledgebase (PharmGKB; http://www.pharmgkb.org) is one of the foremost worldwide resources for PGx knowledge, and the organization has been adapting and refocusing its mission along with the current revolution in genomic medicine. The PharmGKB website provides a diverse array of PGx information, from annotations of the primary literature to guidelines for adjusting drug treatment based on genetic information. It is freely available and accessible to everyone from researchers to clinicians to everyday citizens. PharmGKB was found over 17 years ago, but continues to be a vital resource for the entire PGx community and the general public. Translational, Genomic, and Systems Medicine > Translational Medicine;
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spelling pubmed-60029212018-07-01 PharmGKB: A worldwide resource for pharmacogenomic information Barbarino, Julia M. Whirl‐Carrillo, Michelle Altman, Russ B. Klein, Teri E. Wiley Interdiscip Rev Syst Biol Med Advanced Review As precision medicine becomes increasingly relevant in healthcare, the field of pharmacogenomics (PGx) also continues to gain prominence in the clinical setting. Leading institutions have begun to implement PGx testing and the amount of published PGx literature increases yearly. The Pharmacogenomics Knowledgebase (PharmGKB; http://www.pharmgkb.org) is one of the foremost worldwide resources for PGx knowledge, and the organization has been adapting and refocusing its mission along with the current revolution in genomic medicine. The PharmGKB website provides a diverse array of PGx information, from annotations of the primary literature to guidelines for adjusting drug treatment based on genetic information. It is freely available and accessible to everyone from researchers to clinicians to everyday citizens. PharmGKB was found over 17 years ago, but continues to be a vital resource for the entire PGx community and the general public. Translational, Genomic, and Systems Medicine > Translational Medicine; John Wiley & Sons, Inc. 2018-02-23 2018 /pmc/articles/PMC6002921/ /pubmed/29474005 http://dx.doi.org/10.1002/wsbm.1417 Text en © 2018 The Authors. WIREs Systems Biology and Medicine published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Advanced Review
Barbarino, Julia M.
Whirl‐Carrillo, Michelle
Altman, Russ B.
Klein, Teri E.
PharmGKB: A worldwide resource for pharmacogenomic information
title PharmGKB: A worldwide resource for pharmacogenomic information
title_full PharmGKB: A worldwide resource for pharmacogenomic information
title_fullStr PharmGKB: A worldwide resource for pharmacogenomic information
title_full_unstemmed PharmGKB: A worldwide resource for pharmacogenomic information
title_short PharmGKB: A worldwide resource for pharmacogenomic information
title_sort pharmgkb: a worldwide resource for pharmacogenomic information
topic Advanced Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002921/
https://www.ncbi.nlm.nih.gov/pubmed/29474005
http://dx.doi.org/10.1002/wsbm.1417
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