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Measuring associations between the microbiota and repeated measures of continuous clinical variables using a lasso-penalized generalized linear mixed model
BACKGROUND: Human microbiome studies in clinical settings generally focus on distinguishing the microbiota in health from that in disease at a specific point in time. However, microbiome samples may be associated with disease severity or continuous clinical health indicators that are often assessed...
Autores principales: | Tipton, Laura, Cuenco, Karen T., Huang, Laurence, Greenblatt, Ruth M., Kleerup, Eric, Sciurba, Frank, Duncan, Steven R., Donahoe, Michael P., Morris, Alison, Ghedin, Elodie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003033/ https://www.ncbi.nlm.nih.gov/pubmed/29983746 http://dx.doi.org/10.1186/s13040-018-0173-9 |
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