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Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts
BACKGROUND: Cancer-associated fibroblasts (CAFs) are one of the most important components of tumor stroma and play a key role in modulating tumor growth. However, a mechanistic understanding of how CAFs communicate with tumor cells to promote their proliferation and invasion is far from complete. A...
Autores principales: | Wu, Xinyan, Zahari, Muhammad Saddiq, Renuse, Santosh, Sahasrabuddhe, Nandini A., Chaerkady, Raghothama, Kim, Min-Sik, Fackler, Mary Jo, Stampfer, Martha, Gabrielson, Edward, Sukumar, Saraswati, Pandey, Akhilesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003199/ https://www.ncbi.nlm.nih.gov/pubmed/29946230 http://dx.doi.org/10.1186/s12014-018-9197-x |
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