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Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response
Vaccination in the developing world is hampered by limited patient access, which prevents individuals from receiving the multiple injections necessary for protective immunity. Here, we developed an injectable microparticle formulation of the inactivated polio vaccine (IPV) that releases multiple pul...
Autores principales: | Tzeng, Stephany Y., McHugh, Kevin J., Behrens, Adam M., Rose, Sviatlana, Sugarman, James L., Ferber, Shiran, Langer, Robert, Jaklenec, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003376/ https://www.ncbi.nlm.nih.gov/pubmed/29784798 http://dx.doi.org/10.1073/pnas.1720970115 |
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