Cargando…
Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion
Clumping factor A (ClfA), a cell-wall–anchored protein from Staphylococcus aureus, is a virulence factor in various infections and facilitates the colonization of protein-coated biomaterials. ClfA promotes bacterial adhesion to the blood plasma protein fibrinogen (Fg) via molecular forces that have...
Autores principales: | Herman-Bausier, Philippe, Labate, Cristina, Towell, Aisling M., Derclaye, Sylvie, Geoghegan, Joan A., Dufrêne, Yves F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003445/ https://www.ncbi.nlm.nih.gov/pubmed/29735708 http://dx.doi.org/10.1073/pnas.1718104115 |
Ejemplares similares
-
Force-Induced Strengthening of the Interaction between Staphylococcus aureus Clumping Factor B and Loricrin
por: Vitry, Pauline, et al.
Publicado: (2017) -
Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus
por: da Costa, Thaina M., et al.
Publicado: (2022) -
Staphylococcus aureus Fibronectin-Binding Protein A Mediates Cell-Cell Adhesion through Low-Affinity Homophilic Bonds
por: Herman-Bausier, Philippe, et al.
Publicado: (2015) -
Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target
por: Lacey, Keenan A., et al.
Publicado: (2019) -
Bacterial pathogens under high-tension: Staphylococcus aureus adhesion to von Willebrand factor is activated by force
por: Viela, Felipe, et al.
Publicado: (2019)