Cargando…

Metabolite profiling identifies a signature of tumorigenicity in hepatocellular carcinoma

HCC (Hepatocellular carcinoma) cells exhibit greater metabolic plasticity than normal hepatocytes since they must survive in a dynamic microenvironment where nutrients and oxygen are often scarce. Using a metabolomic approach combined with functional in vitro and in vivo assays, we aimed to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cassim, Shamir, Raymond, Valérie-Ann, Lacoste, Benoit, Lapierre, Pascal, Bilodeau, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003570/ https://www.ncbi.nlm.nih.gov/pubmed/29928490 http://dx.doi.org/10.18632/oncotarget.25525

Ejemplares similares

Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties
por: Lacoste, Benoit, et al.
Publicado: (2017)

Protection against Acute Hepatocellular Injury Afforded by Liver Fibrosis Is Independent of T Lymphocytes
por: Lacoste, Benoit, et al.
Publicado: (2016)

From in vivo to in vitro: Major metabolic alterations take place in hepatocytes during and following isolation
por: Cassim, Shamir, et al.
Publicado: (2017)

Novel Immunotherapies for Autoimmune Hepatitis
por: Cassim, Shamir, et al.
Publicado: (2017)

Upregulation of Krebs cycle and anaerobic glycolysis activity early after onset of liver ischemia
por: Chan, Tom S., et al.
Publicado: (2018)

Metabolomics-Guided Identification of a Distinctive Hepatocellular Carcinoma Signature
por: Tambay, Vincent, et al.
Publicado: (2023)

Bioinformatics profiling identifies seven immune-related risk signatures for hepatocellular carcinoma
por: Xue, Feng, et al.
Publicado: (2020)

Scutellaria barbata Inhibits Hepatocellular Carcinoma Tumorigenicity by Inducing Ferroptosis of Hepatocellular Carcinoma Cells
por: Li, Yue, et al.
Publicado: (2022)

Identification of cellular genes and pathways important for tumorigenicity of hepatocellular carcinoma cell lines by proteomic profiling
por: Zamani, Ali, et al.
Publicado: (2017)

Immune-Mediated Hepatitis During Immune Checkpoint Inhibitor cancer Immunotherapy: Lessons From Autoimmune Hepatitis and Liver Immunology
por: Hercun, Julian, et al.
Publicado: (2022)

Overexpression of SIRT6 attenuates the tumorigenicity of hepatocellular carcinoma cells
por: Wang, Yadong, et al.
Publicado: (2017)

Effects of STC1 overexpression on tumorigenicity and metabolism of hepatocellular carcinoma
por: Leung, Cherry CT, et al.
Publicado: (2017)

Downregulation of SETD5 Suppresses the Tumorigenicity of Hepatocellular Carcinoma Cells
por: Park, Mijin, et al.
Publicado: (2022)

CTHRC1 activates pro-tumorigenic signaling pathways in hepatocellular carcinoma
por: Wang, Yunpeng, et al.
Publicado: (2017)

Corrigendum to: Downregulation of SETD5 Suppresses the Tumorigenicity of Hepatocellular Carcinoma Cells
por: Park, Mijin, et al.
Publicado: (2022)

Profiles of prognostic alternative splicing signature in hepatocellular carcinoma
por: Wu, Fangming, et al.
Publicado: (2020)

Dynamic Tumorigenic Trajectory and Transitional Signatures of Oncogenic Evolution by Single-Cell Transcriptomic Profiling of Esophageal Squamous Cell Carcinoma
por: Liu, Hui, et al.
Publicado: (2021)

Genomewide transcriptomic profiling identifies a gene signature for predicting recurrence in early‐stage hepatocellular carcinoma
por: Kakisaka, Tatsuhiko, et al.
Publicado: (2021)

MYC Rules: Leading Glutamine Metabolism toward a Distinct Cancer Cell Phenotype
por: Tambay, Vincent, et al.
Publicado: (2021)

miR-222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma
por: Liu, Kai, et al.
Publicado: (2021)

Inhibition of Hepatic Stellate Cell Activation Suppresses Tumorigenicity of Hepatocellular Carcinoma in Mice
por: Kang, Min-Jung, et al.
Publicado: (2021)

Differentiating Hepatocellular Carcinoma from Hepatitis C Using Metabolite Profiling
por: Wei, Siwei, et al.
Publicado: (2012)

Overexpression of SMOC2 Attenuates the Tumorigenicity of Hepatocellular Carcinoma Cells and Is Associated With a Positive Postoperative Prognosis in Human Hepatocellular Carcinoma
por: Huang, Xu-Qiong, et al.
Publicado: (2017)

Integrin-Linked Kinase Overexpression and Its Oncogenic Role in Promoting Tumorigenicity of Hepatocellular Carcinoma
por: Chan, Jenny, et al.
Publicado: (2011)

Anti-Cadherin-17 Antibody Modulates Beta-Catenin Signaling and Tumorigenicity of Hepatocellular Carcinoma
por: Wang, Yonggang, et al.
Publicado: (2013)

Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma
por: Wu, Bo, et al.
Publicado: (2015)

The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma
por: Chen, Jia-Jie, et al.
Publicado: (2015)

Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response
por: Cassim, Shamir, et al.
Publicado: (2019)

Antibody-based proteomics to identify an apoptosis signature for early recurrence of hepatocellular carcinoma
por: Morofuji, Noriaki, et al.
Publicado: (2016)

Multi-Omics Analyses Identify Signatures in Patients with Liver Cirrhosis and Hepatocellular Carcinoma
por: Lai, Ming-Wei, et al.
Publicado: (2022)

mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma
por: Serra, Marina, et al.
Publicado: (2022)

Overexpression of zinc finger protein 687 enhances tumorigenic capability and promotes recurrence of hepatocellular carcinoma
por: Zhang, T, et al.
Publicado: (2017)

Heat shock protein 70 downregulation inhibits proliferation, migration and tumorigenicity in hepatocellular carcinoma cells
por: Xiong, Ju, et al.
Publicado: (2017)

Loss of PDK4 expression promotes proliferation, tumorigenicity, motility and invasion of hepatocellular carcinoma cells
por: Qin, Yu-Juan, et al.
Publicado: (2020)

NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma
por: Vandierendonck, Astrid, et al.
Publicado: (2021)

Identification of a gene set that maintains tumorigenicity of the hepatocellular carcinoma cell line Li-7
por: Seyama, Yusuke, et al.
Publicado: (2023)

Systematic profiling of a novel prognostic alternative splicing signature in hepatocellular carcinoma
por: Zhang, Dong, et al.
Publicado: (2019)

Glycolysis gene expression profilings screen for prognostic risk signature of hepatocellular carcinoma
por: Jiang, Longyang, et al.
Publicado: (2019)

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
por: Schulze, Kornelius, et al.
Publicado: (2015)

NELFE-Dependent MYC Signature Identifies a Unique Cancer Subtype in Hepatocellular Carcinoma
por: Dang, Hien, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4amqkm08gri09tvhfppo54a3ch