Cargando…
Activation recovery interval imaging of premature ventricular contraction
Dispersion of ventricular repolarization due to abnormal activation contributes to the susceptibility to cardiac arrhythmias. However, the global pattern of repolarization is difficult to assess clinically. Activation recovery interval (ARI) has been used to understand the properties of ventricular...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003683/ https://www.ncbi.nlm.nih.gov/pubmed/29906289 http://dx.doi.org/10.1371/journal.pone.0196916 |
_version_ | 1783332392042233856 |
---|---|
author | Yang, Ting Yu, Long Jin, Qi Wu, Liqun He, Bin |
author_facet | Yang, Ting Yu, Long Jin, Qi Wu, Liqun He, Bin |
author_sort | Yang, Ting |
collection | PubMed |
description | Dispersion of ventricular repolarization due to abnormal activation contributes to the susceptibility to cardiac arrhythmias. However, the global pattern of repolarization is difficult to assess clinically. Activation recovery interval (ARI) has been used to understand the properties of ventricular repolarization. In this study, we developed an ARI imaging technique to noninvasively reconstruct three-dimensional (3D) ARI maps in 10 premature ventricular contraction (PVC) patients and evaluated the results with the endocardial ARI maps recorded by a clinical navigation system (CARTO). From the analysis results of a total of 100 PVC beats in 10 patients, the average correlation coefficient is 0.86±0.05 and the average relative error is 0.06±0.03. The average localization error is 4.5±2.3 mm between the longest ARI sites in 3D ARI maps and those in CARTO endocardial ARI maps. The present results suggest that ARI imaging could serve as an alternative of evaluating global pattern of ventricular repolarization noninvasively and could assist in the future investigation of the relationship between global repolarization dispersion and the susceptibility to cardiac arrhythmias. |
format | Online Article Text |
id | pubmed-6003683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-60036832018-06-25 Activation recovery interval imaging of premature ventricular contraction Yang, Ting Yu, Long Jin, Qi Wu, Liqun He, Bin PLoS One Research Article Dispersion of ventricular repolarization due to abnormal activation contributes to the susceptibility to cardiac arrhythmias. However, the global pattern of repolarization is difficult to assess clinically. Activation recovery interval (ARI) has been used to understand the properties of ventricular repolarization. In this study, we developed an ARI imaging technique to noninvasively reconstruct three-dimensional (3D) ARI maps in 10 premature ventricular contraction (PVC) patients and evaluated the results with the endocardial ARI maps recorded by a clinical navigation system (CARTO). From the analysis results of a total of 100 PVC beats in 10 patients, the average correlation coefficient is 0.86±0.05 and the average relative error is 0.06±0.03. The average localization error is 4.5±2.3 mm between the longest ARI sites in 3D ARI maps and those in CARTO endocardial ARI maps. The present results suggest that ARI imaging could serve as an alternative of evaluating global pattern of ventricular repolarization noninvasively and could assist in the future investigation of the relationship between global repolarization dispersion and the susceptibility to cardiac arrhythmias. Public Library of Science 2018-06-15 /pmc/articles/PMC6003683/ /pubmed/29906289 http://dx.doi.org/10.1371/journal.pone.0196916 Text en © 2018 Yang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Yang, Ting Yu, Long Jin, Qi Wu, Liqun He, Bin Activation recovery interval imaging of premature ventricular contraction |
title | Activation recovery interval imaging of premature ventricular contraction |
title_full | Activation recovery interval imaging of premature ventricular contraction |
title_fullStr | Activation recovery interval imaging of premature ventricular contraction |
title_full_unstemmed | Activation recovery interval imaging of premature ventricular contraction |
title_short | Activation recovery interval imaging of premature ventricular contraction |
title_sort | activation recovery interval imaging of premature ventricular contraction |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003683/ https://www.ncbi.nlm.nih.gov/pubmed/29906289 http://dx.doi.org/10.1371/journal.pone.0196916 |
work_keys_str_mv | AT yangting activationrecoveryintervalimagingofprematureventricularcontraction AT yulong activationrecoveryintervalimagingofprematureventricularcontraction AT jinqi activationrecoveryintervalimagingofprematureventricularcontraction AT wuliqun activationrecoveryintervalimagingofprematureventricularcontraction AT hebin activationrecoveryintervalimagingofprematureventricularcontraction |