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Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis

Viruses from the Coronaviridae, Togaviridae, and Hepeviridae families ​all contain genes that encode a conserved protein domain, called a macrodomain; however, the role of this domain during infection has remained enigmatic. The recent discovery that mammalian macrodomain proteins enzymatically remo...

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Detalles Bibliográficos
Autores principales: Fehr, Anthony R., Jankevicius, Gytis, Ahel, Ivan, Perlman, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003825/
https://www.ncbi.nlm.nih.gov/pubmed/29268982
http://dx.doi.org/10.1016/j.tim.2017.11.011