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Duplication of a germline promoter downstream of the IgH 3′ regulatory region impairs class switch recombination

During an adaptive immune response, B cells can change their surface immunoglobulins from IgM to IgG, IgE or IgA through a process called class switch recombination (CSR). Switching is preceded by inducible non-coding germline transcription (GLT) of the selected constant gene(s), which is largely co...

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Detalles Bibliográficos
Autores principales:	Santos, Joana M., Braikia, Fatima-Zohra, Oudinet, Chloé, Haddad, Dania, Conte, Caroline, Dauba, Audrey, Khamlichi, Ahmed Amine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003904/ https://www.ncbi.nlm.nih.gov/pubmed/29907762 http://dx.doi.org/10.1038/s41598-018-27448-4

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