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Strontium ranelate promotes odonto-/osteogenic differentiation/mineralization of dental papillae cells in vitro and mineralized tissue formation of the dental pulp in vivo

This study examined the effects and mechanisms of strontium ranelate (SrRn)—a drug used to treat osteoporosis—on the proliferation and differentiation/mineralization of cloned dental pulp-like cells (mouse dental papillae cells; MDPs). It also determined whether topical application of SrRn to expose...

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Detalles Bibliográficos
Autores principales: Bakhit, Alamuddin, Kawashima, Nobuyuki, Hashimoto, Kentaro, Noda, Sonoko, Nara, Keisuke, Kuramoto, Masashi, Tazawa, Kento, Okiji, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003917/
https://www.ncbi.nlm.nih.gov/pubmed/29907831
http://dx.doi.org/10.1038/s41598-018-27461-7