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Nanoscale metal-organic frameworks enhance radiotherapy to potentiate checkpoint blockade immunotherapy
Checkpoint blockade immunotherapy enhances systemic antitumor immune response by targeting T cell inhibitory pathways; however, inadequate T cell infiltration has limited its anticancer efficacy. Radiotherapy (RT) has local immunomodulatory effects that can alter the microenvironment of irradiated t...
Autores principales: | Ni, Kaiyuan, Lan, Guangxu, Chan, Christina, Quigley, Bryan, Lu, Kuangda, Aung, Theint, Guo, Nining, La Riviere, Patrick, Weichselbaum, Ralph R., Lin, Wenbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003951/ https://www.ncbi.nlm.nih.gov/pubmed/29907739 http://dx.doi.org/10.1038/s41467-018-04703-w |
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