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Diagnosis of Human Leptospirosis in a Clinical Setting: Real-Time PCR High Resolution Melting Analysis for Detection of Leptospira at the Onset of Disease
Currently, direct detection of Leptospira can be done in clinical laboratories by conventional and by real-time PCR (qRT-PCR). We tested a biobank of paired samples of serum and urine from the same patient (202 patients) presenting at the hospital in an area endemic for leptospirosis using qRT-PCR f...
Autores principales: | Esteves, Lisa M., Bulhões, Sara M., Branco, Claudia C., Carreira, Teresa, Vieira, Maria L., Gomes-Solecki, Maria, Mota-Vieira, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003994/ https://www.ncbi.nlm.nih.gov/pubmed/29907838 http://dx.doi.org/10.1038/s41598-018-27555-2 |
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