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A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs
Circular RNAs (circRNAs) are generated from many protein-coding genes. Most accumulate in the cytoplasm, but how circRNA localization or nuclear export is controlled remains unclear. Using RNAi screening, we found that depletion of the Drosophila DExH/D-box helicase Hel25E results in nuclear accumul...
Autores principales: | Huang, Chuan, Liang, Dongming, Tatomer, Deirdre C., Wilusz, Jeremy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004072/ https://www.ncbi.nlm.nih.gov/pubmed/29773557 http://dx.doi.org/10.1101/gad.314856.118 |
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