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A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs

Circular RNAs (circRNAs) are generated from many protein-coding genes. Most accumulate in the cytoplasm, but how circRNA localization or nuclear export is controlled remains unclear. Using RNAi screening, we found that depletion of the Drosophila DExH/D-box helicase Hel25E results in nuclear accumul...

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Detalles Bibliográficos
Autores principales: Huang, Chuan, Liang, Dongming, Tatomer, Deirdre C., Wilusz, Jeremy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004072/
https://www.ncbi.nlm.nih.gov/pubmed/29773557
http://dx.doi.org/10.1101/gad.314856.118

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