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The impact of mitotic errors on cell proliferation and tumorigenesis

Mitosis is a delicate event that must be executed with high fidelity to ensure genomic stability. Recent work has provided insight into how mitotic errors shape cancer genomes by driving both numerical and structural alterations in chromosomes that contribute to tumor initiation and progression. Her...

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Detalles Bibliográficos
Autores principales: Levine, Michelle S., Holland, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004076/
https://www.ncbi.nlm.nih.gov/pubmed/29802124
http://dx.doi.org/10.1101/gad.314351.118