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The impact of mitotic errors on cell proliferation and tumorigenesis
Mitosis is a delicate event that must be executed with high fidelity to ensure genomic stability. Recent work has provided insight into how mitotic errors shape cancer genomes by driving both numerical and structural alterations in chromosomes that contribute to tumor initiation and progression. Her...
Autores principales: | Levine, Michelle S., Holland, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004076/ https://www.ncbi.nlm.nih.gov/pubmed/29802124 http://dx.doi.org/10.1101/gad.314351.118 |
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