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Colistin causes profound morphological alteration but minimal cytoplasmic membrane perforation in populations of Escherichia coli and Pseudomonas aeruginosa

Whilst colistin (polymyxin E) represents the last mainstream treatment option for multidrug-resistant Gram-negative pathogens, details of its mechanism of action remain to be fully resolved. In this study, the effects of sub-inhibitory, inhibitory-bactericidal, and supra-bactericidal levels of colis...

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Detalles Bibliográficos
Autores principales:	O’Driscoll, Noëlle H., Cushnie, T. P. Tim, Matthews, Kerr H., Lamb, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004271/ https://www.ncbi.nlm.nih.gov/pubmed/29423561 http://dx.doi.org/10.1007/s00203-018-1485-3

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