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XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation
In order to investigate the molecular mechanisms by which the oncogenic mutant KIT/D816V causes transformation of cells, we investigated proteins that selectively bind KIT/D816V, but not wild-type KIT, as potential mediators of transformation. By mass spectrometry several proteins were identified, a...
Autores principales: | Sun, Jianmin, Thingholm, Tine, Højrup, Peter, Rönnstrand, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004359/ https://www.ncbi.nlm.nih.gov/pubmed/29910466 http://dx.doi.org/10.1038/s41389-018-0057-3 |
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