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Myeloid-Derived Suppressor Cells Hinder the Anti-Cancer Activity of Immune Checkpoint Inhibitors

Immune checkpoint inhibitors (ICI) used for cancer immunotherapy were shown to boost the existing anti-tumor immune response by preventing the inhibition of T cells by tumor cells. Antibodies targeting two negative immune checkpoint pathways, namely cytotoxic T-lymphocyte-associated protein 4 (CTLA-...

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Detalles Bibliográficos
Autores principales:	Weber, Rebekka, Fleming, Viktor, Hu, Xiaoying, Nagibin, Vasyl, Groth, Christopher, Altevogt, Peter, Utikal, Jochen, Umansky, Viktor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004385/ https://www.ncbi.nlm.nih.gov/pubmed/29942309 http://dx.doi.org/10.3389/fimmu.2018.01310

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