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DN2 Thymocytes Activate a Specific Robust DNA Damage Response to Ionizing Radiation-Induced DNA Double-Strand Breaks

For successful bone marrow transplantation (BMT), a preconditioning regime involving chemo and radiotherapy is used that results in DNA damage to both hematopoietic and stromal elements. Following radiation exposure, it is well recognized that a single wave of host-derived thymocytes reconstitutes t...

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Detalles Bibliográficos
Autores principales:	Calvo-Asensio, Irene, Sugrue, Tara, Bosco, Nabil, Rolink, Antonius, Ceredig, Rhodri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004388/ https://www.ncbi.nlm.nih.gov/pubmed/29942310 http://dx.doi.org/10.3389/fimmu.2018.01312

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