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Are Amyloid Fibrils RNA-Traps? A Molecular Dynamics Perspective

The self-assembly of proteins and peptides into amyloids is a key feature of an increasing number of diseases. Amyloid fibrils display a unique surface reactivity endowing the sequestration of molecules such as MicroRNAs, which can be the active moiety of the toxic action. To test this hypothesis we...

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Detalles Bibliográficos
Autores principales:	Meli, Massimiliano, Gasset, Maria, Colombo, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004406/ https://www.ncbi.nlm.nih.gov/pubmed/29942805 http://dx.doi.org/10.3389/fmolb.2018.00053

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