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The neuron-specific formin Delphilin nucleates nonmuscle actin but does not enhance elongation
The formin Delphilin binds the glutamate receptor, GluRδ2, in dendritic spines of Purkinje cells. Both proteins play a role in learning. To understand how Delphilin functions in neurons, we studied the actin assembly properties of this formin. Formins have a conserved formin homology 2 domain, which...
Autores principales: | Silkworth, William T., Kunes, Kristina L., Nickel, Grace C., Phillips, Martin L., Quinlan, Margot E., Vizcarra, Christina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004577/ https://www.ncbi.nlm.nih.gov/pubmed/29282276 http://dx.doi.org/10.1091/mbc.E17-06-0363 |
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