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PICK1 is essential for insulin production and the maintenance of glucose homeostasis
Protein interacting with C-kinase 1 (PICK1) is a peripheral membrane protein that controls insulin granule formation, trafficking, and maturation in INS-1E cells. However, global Pick1-knockout mice showed only a subtle diabetes-like phenotype. This raises the possibility that compensatory effects f...
Autores principales: | Li, Jia, Mao, Zhuo, Huang, Jiandong, Xia, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004578/ https://www.ncbi.nlm.nih.gov/pubmed/29298842 http://dx.doi.org/10.1091/mbc.E17-03-0204 |
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