Cargando…

PICK1 is essential for insulin production and the maintenance of glucose homeostasis

Protein interacting with C-kinase 1 (PICK1) is a peripheral membrane protein that controls insulin granule formation, trafficking, and maturation in INS-1E cells. However, global Pick1-knockout mice showed only a subtle diabetes-like phenotype. This raises the possibility that compensatory effects f...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jia, Mao, Zhuo, Huang, Jiandong, Xia, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004578/
https://www.ncbi.nlm.nih.gov/pubmed/29298842
http://dx.doi.org/10.1091/mbc.E17-03-0204

Ejemplares similares