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S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms

S100A4, a member of the S100 family of Ca(2+)-binding proteins, is a key regulator of cell migration and invasion. Our previous studies showed that bone marrow–derived macrophages from S100A4(−/−) mice exhibit defects in directional motility and chemotaxis in vitro and reduced recruitment to sites o...

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Detalles Bibliográficos
Autores principales: Dulyaninova, Natalya G., Ruiz, Penelope D., Gamble, Matthew J., Backer, Jonathan M., Bresnick, Anne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004585/
https://www.ncbi.nlm.nih.gov/pubmed/29282275
http://dx.doi.org/10.1091/mbc.E17-07-0460