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Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR

OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic labor...

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Autores principales: Phouangsouvanh, Savandalath, Mayxay, Mayfong, Keoluangkhot, Valy, Vongsouvath, Manivanh, Davong, Viengmon, Dance, David A.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004598/
https://www.ncbi.nlm.nih.gov/pubmed/29229280
http://dx.doi.org/10.1016/j.jgar.2017.12.001
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author Phouangsouvanh, Savandalath
Mayxay, Mayfong
Keoluangkhot, Valy
Vongsouvath, Manivanh
Davong, Viengmon
Dance, David A.B.
author_facet Phouangsouvanh, Savandalath
Mayxay, Mayfong
Keoluangkhot, Valy
Vongsouvath, Manivanh
Davong, Viengmon
Dance, David A.B.
author_sort Phouangsouvanh, Savandalath
collection PubMed
description OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic laboratory in Vientiane, Laos, between 2011 and 2015. Susceptibility to five antibiotics was determined by the standard disk diffusion method for 158 of the isolates. RESULTS: Rates of resistance to penicillin (by β-lactamase production), tetracycline and ciprofloxacin were 89.9%, 99.4% and 84.8%, respectively. All isolates were susceptible to ceftriaxone and spectinomycin. CONCLUSIONS: The situation in Laos is similar to that in neighbouring countries; this fortunately means that the latest Lao national guidelines for treating gonorrhoea should still be effective.
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spelling pubmed-60045982018-06-19 Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR Phouangsouvanh, Savandalath Mayxay, Mayfong Keoluangkhot, Valy Vongsouvath, Manivanh Davong, Viengmon Dance, David A.B. J Glob Antimicrob Resist Article OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic laboratory in Vientiane, Laos, between 2011 and 2015. Susceptibility to five antibiotics was determined by the standard disk diffusion method for 158 of the isolates. RESULTS: Rates of resistance to penicillin (by β-lactamase production), tetracycline and ciprofloxacin were 89.9%, 99.4% and 84.8%, respectively. All isolates were susceptible to ceftriaxone and spectinomycin. CONCLUSIONS: The situation in Laos is similar to that in neighbouring countries; this fortunately means that the latest Lao national guidelines for treating gonorrhoea should still be effective. Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer 2018-06 /pmc/articles/PMC6004598/ /pubmed/29229280 http://dx.doi.org/10.1016/j.jgar.2017.12.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Phouangsouvanh, Savandalath
Mayxay, Mayfong
Keoluangkhot, Valy
Vongsouvath, Manivanh
Davong, Viengmon
Dance, David A.B.
Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title_full Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title_fullStr Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title_full_unstemmed Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title_short Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
title_sort antimicrobial susceptibility of neisseria gonorrhoeae isolates in vientiane, lao pdr
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004598/
https://www.ncbi.nlm.nih.gov/pubmed/29229280
http://dx.doi.org/10.1016/j.jgar.2017.12.001
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