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Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR
OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic labor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004598/ https://www.ncbi.nlm.nih.gov/pubmed/29229280 http://dx.doi.org/10.1016/j.jgar.2017.12.001 |
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author | Phouangsouvanh, Savandalath Mayxay, Mayfong Keoluangkhot, Valy Vongsouvath, Manivanh Davong, Viengmon Dance, David A.B. |
author_facet | Phouangsouvanh, Savandalath Mayxay, Mayfong Keoluangkhot, Valy Vongsouvath, Manivanh Davong, Viengmon Dance, David A.B. |
author_sort | Phouangsouvanh, Savandalath |
collection | PubMed |
description | OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic laboratory in Vientiane, Laos, between 2011 and 2015. Susceptibility to five antibiotics was determined by the standard disk diffusion method for 158 of the isolates. RESULTS: Rates of resistance to penicillin (by β-lactamase production), tetracycline and ciprofloxacin were 89.9%, 99.4% and 84.8%, respectively. All isolates were susceptible to ceftriaxone and spectinomycin. CONCLUSIONS: The situation in Laos is similar to that in neighbouring countries; this fortunately means that the latest Lao national guidelines for treating gonorrhoea should still be effective. |
format | Online Article Text |
id | pubmed-6004598 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer |
record_format | MEDLINE/PubMed |
spelling | pubmed-60045982018-06-19 Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR Phouangsouvanh, Savandalath Mayxay, Mayfong Keoluangkhot, Valy Vongsouvath, Manivanh Davong, Viengmon Dance, David A.B. J Glob Antimicrob Resist Article OBJECTIVES: The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates in the Lao People’s Democratic Republic (Laos). METHODS: A total of 165 gonococcal isolates (1.3%) were obtained from 12 281 genital samples routinely submitted to a diagnostic laboratory in Vientiane, Laos, between 2011 and 2015. Susceptibility to five antibiotics was determined by the standard disk diffusion method for 158 of the isolates. RESULTS: Rates of resistance to penicillin (by β-lactamase production), tetracycline and ciprofloxacin were 89.9%, 99.4% and 84.8%, respectively. All isolates were susceptible to ceftriaxone and spectinomycin. CONCLUSIONS: The situation in Laos is similar to that in neighbouring countries; this fortunately means that the latest Lao national guidelines for treating gonorrhoea should still be effective. Published by Elsevier Ltd. on behalf of International Society of Chemotherapy for Infection and Cancer 2018-06 /pmc/articles/PMC6004598/ /pubmed/29229280 http://dx.doi.org/10.1016/j.jgar.2017.12.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Phouangsouvanh, Savandalath Mayxay, Mayfong Keoluangkhot, Valy Vongsouvath, Manivanh Davong, Viengmon Dance, David A.B. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title_full | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title_fullStr | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title_full_unstemmed | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title_short | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates in Vientiane, Lao PDR |
title_sort | antimicrobial susceptibility of neisseria gonorrhoeae isolates in vientiane, lao pdr |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004598/ https://www.ncbi.nlm.nih.gov/pubmed/29229280 http://dx.doi.org/10.1016/j.jgar.2017.12.001 |
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