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Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells

Sphingosine kinase 1 (SphK1) is a master kinase that catalyzes the synthesis of sphingosine 1 phosphate and participates in the regulation of cell proliferation and autophagy. The present study aimed to assess the effects of the activation of the SphK1/extracellular signal-regulated kinase (ERK)/pho...

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Detalles Bibliográficos
Autores principales: Xu, Chunyan, Zhang, Wenlu, Liu, Shiquan, Wu, Wenhong, Qin, Mengbin, Huang, Jiean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004663/
https://www.ncbi.nlm.nih.gov/pubmed/29928348
http://dx.doi.org/10.3892/ol.2018.8588

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