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PI3K/AKT inhibition induces compensatory activation of the MET/STAT3 pathway in non-small cell lung cancer

Constitutive activation of the phosphoinositide 3-kinase (PI3K)/AKT signaling pathway is evident in a diverse array of human cancer types, and targeting the pathway is an attractive therapeutic approach. However, pre-clinical and clinical studies have demonstrated that the antitumor efficacy of a nu...

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Detalles Bibliográficos
Autores principales:	Bian, Chunan, Liu, Zonghang, Li, Dakou, Zhen, Lifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004714/ https://www.ncbi.nlm.nih.gov/pubmed/29928341 http://dx.doi.org/10.3892/ol.2018.8587

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