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Future directions of resveratrol research

Resveratrol improves healthspan and lifespan in many organisms. Several different targets and mechanisms of action have been proposed to explain the beneficial effects of resveratrol on healthspan and longevity, including the activation of a family of proteins known as sirtuins and its action as a c...

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Autores principales: Wahl, Devin, Bernier, Michel, Simpson, Stephen J., de Cabo, Rafael, Le Couteur, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004906/
https://www.ncbi.nlm.nih.gov/pubmed/29951589
http://dx.doi.org/10.3233/NHA-170035
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author Wahl, Devin
Bernier, Michel
Simpson, Stephen J.
de Cabo, Rafael
Le Couteur, David G.
author_facet Wahl, Devin
Bernier, Michel
Simpson, Stephen J.
de Cabo, Rafael
Le Couteur, David G.
author_sort Wahl, Devin
collection PubMed
description Resveratrol improves healthspan and lifespan in many organisms. Several different targets and mechanisms of action have been proposed to explain the beneficial effects of resveratrol on healthspan and longevity, including the activation of a family of proteins known as sirtuins and its action as a calorie restriction mimetic. In this mini-review, we discuss some of the most recent findings to date in the resveratrol field and suggest three areas of future research based on those results.
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spelling pubmed-60049062018-06-25 Future directions of resveratrol research Wahl, Devin Bernier, Michel Simpson, Stephen J. de Cabo, Rafael Le Couteur, David G. Nutr Healthy Aging Review Resveratrol improves healthspan and lifespan in many organisms. Several different targets and mechanisms of action have been proposed to explain the beneficial effects of resveratrol on healthspan and longevity, including the activation of a family of proteins known as sirtuins and its action as a calorie restriction mimetic. In this mini-review, we discuss some of the most recent findings to date in the resveratrol field and suggest three areas of future research based on those results. IOS Press 2018-06-15 /pmc/articles/PMC6004906/ /pubmed/29951589 http://dx.doi.org/10.3233/NHA-170035 Text en © 2018 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Wahl, Devin
Bernier, Michel
Simpson, Stephen J.
de Cabo, Rafael
Le Couteur, David G.
Future directions of resveratrol research
title Future directions of resveratrol research
title_full Future directions of resveratrol research
title_fullStr Future directions of resveratrol research
title_full_unstemmed Future directions of resveratrol research
title_short Future directions of resveratrol research
title_sort future directions of resveratrol research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004906/
https://www.ncbi.nlm.nih.gov/pubmed/29951589
http://dx.doi.org/10.3233/NHA-170035
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