The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST)

BACKGROUND: It has been proposed that maternal folic-acid supplement use may alter the DNA-methylation patterns of the offspring during the in-utero period, which could influence development and later-life health outcomes. Evidence from human studies suggests a role for prenatal folate levels in inf...

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Detalles Bibliográficos
Autores principales: Richmond, Rebecca C, Sharp, Gemma C, Herbert, Georgia, Atkinson, Charlotte, Taylor, Caroline, Bhattacharya, Sohinee, Campbell, Doris, Hall, Marion, Kazmi, Nabila, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Davey Smith, George, Ness, Andy, Relton, Caroline L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
DNA Methylation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005053/
https://www.ncbi.nlm.nih.gov/pubmed/29546377
http://dx.doi.org/10.1093/ije/dyy032

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