Cargando…
Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization
Humans show a preference for using the right hand over the left for tasks and activities of everyday life. While experimental work in non-human primates has identified the neural systems responsible for reaching and grasping, the neural basis of lateralized motor behavior in humans remains elusive....
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005057/ https://www.ncbi.nlm.nih.gov/pubmed/29688293 http://dx.doi.org/10.1093/cercor/bhy040 |
_version_ | 1783332635365343232 |
---|---|
author | Howells, Henrietta Thiebaut de Schotten, Michel Dell’Acqua, Flavio Beyh, Ahmad Zappalà, Giuseppe Leslie, Anoushka Simmons, Andrew Murphy, Declan G Catani, Marco |
author_facet | Howells, Henrietta Thiebaut de Schotten, Michel Dell’Acqua, Flavio Beyh, Ahmad Zappalà, Giuseppe Leslie, Anoushka Simmons, Andrew Murphy, Declan G Catani, Marco |
author_sort | Howells, Henrietta |
collection | PubMed |
description | Humans show a preference for using the right hand over the left for tasks and activities of everyday life. While experimental work in non-human primates has identified the neural systems responsible for reaching and grasping, the neural basis of lateralized motor behavior in humans remains elusive. The advent of diffusion imaging tractography for studying connectional anatomy in the living human brain provides the possibility of understanding the relationship between hemispheric asymmetry, hand preference, and manual specialization. In this study, diffusion tractography was used to demonstrate an interaction between hand preference and the asymmetry of frontoparietal tracts, specifically the dorsal branch of the superior longitudinal fasciculus, responsible for visuospatial integration and motor planning. This is in contrast to the corticospinal tract and the superior cerebellar peduncle, for which asymmetry was not related to hand preference. Asymmetry of the dorsal frontoparietal tract was also highly correlated with the degree of lateralization in tasks requiring visuospatial integration and fine motor control. These results suggest a common anatomical substrate for hand preference and lateralized manual specialization in frontoparietal tracts important for visuomotor processing. |
format | Online Article Text |
id | pubmed-6005057 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-60050572018-06-21 Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization Howells, Henrietta Thiebaut de Schotten, Michel Dell’Acqua, Flavio Beyh, Ahmad Zappalà, Giuseppe Leslie, Anoushka Simmons, Andrew Murphy, Declan G Catani, Marco Cereb Cortex Original Articles Humans show a preference for using the right hand over the left for tasks and activities of everyday life. While experimental work in non-human primates has identified the neural systems responsible for reaching and grasping, the neural basis of lateralized motor behavior in humans remains elusive. The advent of diffusion imaging tractography for studying connectional anatomy in the living human brain provides the possibility of understanding the relationship between hemispheric asymmetry, hand preference, and manual specialization. In this study, diffusion tractography was used to demonstrate an interaction between hand preference and the asymmetry of frontoparietal tracts, specifically the dorsal branch of the superior longitudinal fasciculus, responsible for visuospatial integration and motor planning. This is in contrast to the corticospinal tract and the superior cerebellar peduncle, for which asymmetry was not related to hand preference. Asymmetry of the dorsal frontoparietal tract was also highly correlated with the degree of lateralization in tasks requiring visuospatial integration and fine motor control. These results suggest a common anatomical substrate for hand preference and lateralized manual specialization in frontoparietal tracts important for visuomotor processing. Oxford University Press 2018-07 2018-04-21 /pmc/articles/PMC6005057/ /pubmed/29688293 http://dx.doi.org/10.1093/cercor/bhy040 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Howells, Henrietta Thiebaut de Schotten, Michel Dell’Acqua, Flavio Beyh, Ahmad Zappalà, Giuseppe Leslie, Anoushka Simmons, Andrew Murphy, Declan G Catani, Marco Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title | Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title_full | Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title_fullStr | Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title_full_unstemmed | Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title_short | Frontoparietal Tracts Linked to Lateralized Hand Preference and Manual Specialization |
title_sort | frontoparietal tracts linked to lateralized hand preference and manual specialization |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005057/ https://www.ncbi.nlm.nih.gov/pubmed/29688293 http://dx.doi.org/10.1093/cercor/bhy040 |
work_keys_str_mv | AT howellshenrietta frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT thiebautdeschottenmichel frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT dellacquaflavio frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT beyhahmad frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT zappalagiuseppe frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT leslieanoushka frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT simmonsandrew frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT murphydeclang frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization AT catanimarco frontoparietaltractslinkedtolateralizedhandpreferenceandmanualspecialization |