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Genomic evidence that the live Chlamydia abortus vaccine strain 1B is not attenuated and has the potential to cause disease

BACKGROUND: The live, temperature-attenuated vaccine strain 1B of Chlamydia abortus, the aetiological agent of ovine enzootic abortion (OEA), has been implicated in cases of vaccine breakdown. The aim of this study was to understand the nature of this attenuation through sequencing of the vaccine pa...

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Detalles Bibliográficos
Autores principales:	Longbottom, David, Sait, Michelle, Livingstone, Morag, Laroucau, Karine, Sachse, Konrad, Harris, Simon R., Thomson, Nicholas R., Seth-Smith, Helena M.B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005232/ https://www.ncbi.nlm.nih.gov/pubmed/29759381 http://dx.doi.org/10.1016/j.vaccine.2018.05.042

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