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Directing group assisted meta-hydroxylation by C–H activation

meta-Hydroxylated cores are ubiquitous in natural products. Herein, we disclose the first template assisted meta-hydroxylation reaction. Experimental and in silico studies helped us to gain valuable mechanistic insights, including the role of the hexafluoroisopropanol (HFIP) solvent, during C–H hydr...

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Detalles Bibliográficos
Autores principales: Maji, Arun, Bhaskararao, Bangaru, Singha, Santanu, Sunoj, Raghavan B., Maiti, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005269/
https://www.ncbi.nlm.nih.gov/pubmed/29997806
http://dx.doi.org/10.1039/c5sc04060d

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