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Icariside II ameliorates endothelial dysfunction by regulating the MAPK pathway via miR-126/SPRED1 in diabetic human cavernous endothelial cells

AIM: The aim of the study was to investigate whether miR-126, a regulator of MAPK signaling via targeting sprouty-related EVH1 domain-containing protein 1 (SPRED1) mRNA, is involved in the process by which icariside II (ICA II) ameliorates endothelial dysfunction in human cavernous endothelial cells...

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Detalles Bibliográficos
Autores principales:	Lei, Hongen, Li, Huixi, Tian, Long, Li, Meng, Xin, Zhongcheng, Zhang, Xiaodong, Guan, Ruili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005314/ https://www.ncbi.nlm.nih.gov/pubmed/29942117 http://dx.doi.org/10.2147/DDDT.S166734

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