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Betahistine Treatment in a Cat Model of Vestibular Pathology: Pharmacokinetic and Pharmacodynamic Approaches
This study is a pharmacokinetic (PK) and pharmacodynamics (PD) approach using betahistine doses levels in unilateral vestibular neurectomized cats (UVN) comparable to those used in humans for treating patients with Menière's disease. The aim is to investigate for the first time oral betahistine...
Autores principales: | Tighilet, Brahim, Léonard, Jacques, Watabe, Isabelle, Bernard-Demanze, Laurence, Lacour, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005348/ https://www.ncbi.nlm.nih.gov/pubmed/29942281 http://dx.doi.org/10.3389/fneur.2018.00431 |
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