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A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding

Mmi1 is an essential RNA-binding protein in the fission yeast Schizosaccharomyces pombe that eliminates meiotic transcripts during normal vegetative growth. Mmi1 contains a YTH domain that binds specific RNA sequences, targeting mRNAs for degradation. The YTH domain of Mmi1 uses a noncanonical RNA-b...

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Detalles Bibliográficos
Autores principales:	Stowell, James A. W., Wagstaff, Jane L., Hill, Chris H., Yu, Minmin, McLaughlin, Stephen H., Freund, Stefan M. V., Passmore, Lori A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005420/ https://www.ncbi.nlm.nih.gov/pubmed/29695507 http://dx.doi.org/10.1074/jbc.RA118.002291

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