Cargando…

Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS

The crystal structures of a biologically and therapeutically active recombinant homotrimeric fragment of native human SP-D (hSP-D) complexed with the inner core oligosaccharide of the Salmonella enterica sv Minnesota rough strains R5 and R7 (rough mutant chemotypes Rc and Rd1) have been determined....

Descripción completa

Detalles Bibliográficos
Autores principales: Littlejohn, Jamie R., da Silva, Ruben F., Neale, William A., Smallcombe, Carrie C., Clark, Howard W., Mackay, Rose-Marie A., Watson, Alastair S., Madsen, Jens, Hood, Derek W., Burns, Ian, Greenhough, Trevor J., Shrive, Annette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005524/
https://www.ncbi.nlm.nih.gov/pubmed/29912941
http://dx.doi.org/10.1371/journal.pone.0199175