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Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS
The crystal structures of a biologically and therapeutically active recombinant homotrimeric fragment of native human SP-D (hSP-D) complexed with the inner core oligosaccharide of the Salmonella enterica sv Minnesota rough strains R5 and R7 (rough mutant chemotypes Rc and Rd1) have been determined....
Autores principales: | Littlejohn, Jamie R., da Silva, Ruben F., Neale, William A., Smallcombe, Carrie C., Clark, Howard W., Mackay, Rose-Marie A., Watson, Alastair S., Madsen, Jens, Hood, Derek W., Burns, Ian, Greenhough, Trevor J., Shrive, Annette K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005524/ https://www.ncbi.nlm.nih.gov/pubmed/29912941 http://dx.doi.org/10.1371/journal.pone.0199175 |
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