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Structure/function of the soluble guanylyl cyclase catalytic domain
Soluble guanylyl cyclase (GC-1) is the primary receptor of nitric oxide (NO) in smooth muscle cells and maintains vascular function by inducing vasorelaxation in nearby blood vessels. GC-1 converts guanosine 5′-triphosphate (GTP) into cyclic guanosine 3′,5′-monophosphate (cGMP), which acts as a seco...
Autores principales: | Childers, Kenneth C., Garcin, Elsa D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005667/ https://www.ncbi.nlm.nih.gov/pubmed/29702251 http://dx.doi.org/10.1016/j.niox.2018.04.008 |
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