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Structure/function of the soluble guanylyl cyclase catalytic domain

Soluble guanylyl cyclase (GC-1) is the primary receptor of nitric oxide (NO) in smooth muscle cells and maintains vascular function by inducing vasorelaxation in nearby blood vessels. GC-1 converts guanosine 5′-triphosphate (GTP) into cyclic guanosine 3′,5′-monophosphate (cGMP), which acts as a seco...

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Detalles Bibliográficos
Autores principales: Childers, Kenneth C., Garcin, Elsa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005667/
https://www.ncbi.nlm.nih.gov/pubmed/29702251
http://dx.doi.org/10.1016/j.niox.2018.04.008

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